"Vinodji had a rare and profound influence over the masses with his simple and charismatic character," she said, adding the actor dominated the silver screen with his outstanding persona.
Gandhi expressed solidarity with Khanna's family.
Rahul also said that Khanna was an icon for an entire generation of cinema buffs.
"A talented actor and an icon for an entire generation of cinema lovers, Mr Vinod Khanna's passing is indeed a sad loss. Condolences to his family," he said on Twitter.
The veteran actor and BJP MP died of cancer at a Mumbai hospital today.
Khanna was four-time MP from Gurdaspur constituency in Punjab.