The rally is likely to take place in the evening, Congress sources said here.
The meeting is crucial for Congress leaders in Telangana as they have pinned their hopes on Gandhi's campaign to boost the morale of cadres and ward off competition from regional heavyweight TRS and TDP-BJP combine.
It was in Karimnagar that the Congress chief had made pro-Telangana comments several years ago.
Pre-poll surveys by different news channels indicated it may not be a cakewalk for Congress, as expected, though the party-led UPA Government got the Telangana Bill passed.
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Highlighting its role in achieving separate Telangana, TRS now says the "reconstruction" of the new state, which will come into being on June 2, is possible only under its wings.
Congress, however, says it was the party which made the separate statehood dream become a reality and that a "golden Telangana" is possible only with it.
BJP had been consistent in supporting separate Telangana and its alliance with TDP, a major force in Andhra Pradesh, is seen as a potent one.