"Today's Executive Orders push the nation further away from core American values of equality and freedom, sow fear in communities of colour that already face increasing violence, hostility and attacks, and make us and the country less safe - all under the guise of national security," said Suman Raghunathan, executive director of South Asian Americans Leading Together (SAALT).
"Walling off the country will not make us safer. We expect this will be the first in a series of attacks against the freedom of immigrants and communities of color in the United States,"she said.
India is currently the fourth-highest sending country for undocumented immigrants after Mexico, El Salvador, and Guatemala.
"We also know there are significant undocumented immigrants originally from other South Asian countries including Pakistan, Bangladesh, Nepal, and the Indo-Caribbean diaspora," it said.
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The executive order puts South Asian communities under further scrutiny and attack in the US, particularly through the alarming revival of the "Secure Communities" program, which deputises local authorities as immigration agents - a function numerous police chiefs have already spoken out against, it added.
"This policy sends a clear message to immigrants that any contact with the police can lead to deportation, and only serves to spur fear in immigrant communities," SAALT alleged.
SAALT said the Executive Orders also strip federal funding for "sanctuary cities" that refuse to arrest or detain undocumented immigrants living in the U.S.
Many of these places of refuge are located in California, New York, and Chicago: areas with massive South Asian American populations as well as immigrant communities writ large, it noted.