Based on the fictional podcast of the same name, "Homecoming" is described as a political thriller centering on a caseworker at a secret government facility.
Roberts will play the caseworkers supervisor while James will play the role of a soldier, reported Deadline.
The podcasts creators Eli Horowitz and Micah Bloomberg will pen the adaptation.
Sam Esmail is writing and developing "Homecoming" as part of his overall deal with Universal Cable Productions, where he also has "Mr Robot" and is working on a miniseries adaptation of the sci-fi classic "Metropolis".