"I've always actually quite enjoyed playing Serena. I've got a game that disrupts her," Stosur said Wednesday. "You have to have the game. My game matches up well against Serena. I've got the kind of weapons that can bother her."
And the 31-year-old Australian advises rivals to play their own games and keep the pressure on the world number one if they hope to derail her bid for a fifth Slam title in a row when the Flushing Meadows fortnight begins August 31.
"You have to go after it. Whatever it is you do, you have got to bring that at the big moments and make it happen."
Coming off a clay-court title at Bad Gastein, second seed Stosur advanced to the quarter-finals of the WTA and ATP Washington Open with a 6-1, 7-5 victory Wednesday over American Irina Falconi.
And despite Williams leading their career rivalry 8-3 (not counting two Stosur wins by walkover) and having won their past four meetings without dropping a set, Stosur takes confidence from a 2-1 record in their Grand Slam meetings, having lost in the fourth round of the 2010 Australian Open but won 6-2, 6-7 (2/7), 8-6 at the 2010 French Open semi-finals as well as in the US Open final.