A clash broke out on the Veer Chand Patel Path - location of their state unit offices - as supporters of BJP and JD(U) attacked each other in which workers of both sides sustained injuries.
The clash took place after BJP protesters objected to a group of JD(U) workers led by the state unit spokesman Rajiv Ranjan marching towards their office apparently to obstruct their agitation.
Senior BJP leaders including C P Thakur, Sushil Kumar Modi, Rajiv Pratap Rudy and Syed Shahnawaz Hussain were detained at Dak Bunglow chowk, police said.
The buses in which these leaders were being taken away to Gardanibagh stadium was thronged by BJP workers.
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Earlier, the leaders led a protest march from party headquarters to Dak bunglow chowk in the heart of the town.
As the law and order situation appeared to get out of control, District Magistrate N Sarvanan Kumar and Senior Superintendent of Police Manu Maharaj rushed to the spot and pacified the warring groups.
The bandh affected normal life with BJP workers forcing closure of shops, market places and disrupting movement of trains in the districts like Darbhanga and Nalanda - the native district of the Chief Minister, official sources said.
Bandh supporters also blocked roads in Aurangabad, Purnia, Muzaffarpur and other districts.
The day-long bandh has been called by BJP in protest against JD(U) parting ways with it in the wake of the appointment of Gujarat Chief Minister Narendra Modi as BJP's election campaign committee chief. The party was also observing the day as 'Vishasghat Divas'.