The pupils, studying in Intermediate second year (Class XII), were staying in the hostel located on the college premises in Nizampet area.
Last night, the students went on a rampage, accusing the college management of not giving them holidays, and complained of being served low quality food. They also said bathrooms and toilets in the hostel were not being maintained properly, the police said.
Following arguments with the college authorities over these issues, some students locked the main gate at around midnight last night and damaged the furniture, lights and overhead tanks in the premises, they said.
A police official said it was wrong on part of the students to ransack the college's property.
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"If they wanted holidays they could have brought the matter to the notice of government authorities. Their behaviour was not proper," said the official.
Police have not registered any case in connection with the incident, he said.
A student told the media the college officials "targeted" the pupils, who were not even allowed emergency outing.
Some reports said the protesters locked the hostel staff in a room before ransacking the college.