For nearly half of them the angst is so distressing that it makes them want to find a new job.
The research, based on surveys of more than 3,600 employees worldwide, found that Sunday nights are riddled with anxiety for most employees.
Just 22 per cent of those surveyed said they are never nervous about returning to work after a weekend, according to the study by an online job site.
Mary Ellen Slayter, career advice expert for Monster.Com, said with Monday morning being notoriously stressful, she doesn't think anyone is truly happy to see their weekends come to a close, 'BusinessNewsDaily' reported.
"Spend a few minutes preparing for next week: review and prioritise your calendar, assemble materials you expect to be using and tie up every loose end you can," Slater said.