In a filing to the BSE, UPL informed Prabhu resigned as Independent and Non- executive Director with effect from November 7.
Prabhu took oath as the Union Railways Minister on November 9.
"At the next Board meeting of the company, the same will be placed for formal acceptance of the same," UPL said in a filing.
A Chartered Accountant, Prabhu was appointed on board of UPL on January 29, 2013.
"The Board of Directors of the company wish to place on record their sincere appreciation for the support and valuable guidance given by Prabhu during his tenure as director of the company," Company's Chairman and Managing Director said Raju Shroff said.