It could prove to be a major breakthrough in the protracted standoff between the 44-year-old Assange and Sweden, where he is wanted in relation to a 2010 rape allegation.
"Interviewing Assange inside the embassy has been Ecuador's request for four years. Over 1,400 days we have been asking the Swedes to come and interrogate him in our embassy. So it is welcome there has been change of heart and some sign of political will," said Ecuador's foreign minister, Dr Guillaume Long.
Long confirmed that the Swedish attorney general had made a formal request that was being considered, 'The Guardian' reported.
The Australian national has been living inside Ecuador's UK mission for four years after the South American country offered him asylum.
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Assange denies the rape charges and has fought against being extradited to Sweden, saying he fears he would then be transferred to the US to face charges on Wikileaks' activities.
However, the UK Foreign Office has called for the UN decision to be reviewed, saying Assange was staying in the embassy voluntarily and that the UK had a legal duty to extradite himto Sweden.
Long said Ecuador's legal department will now examine Sweden's request and would also want assurances that the UK would not seek to prosecute Assange for avoiding arrest.