The stock debuted at Rs 295, a sharp gain of 18 per cent against the issue price, on BSE even as the broader market remained lacklustre.
Similarly, on NSE, the stock listed at Rs 295 and was later trading at Rs 311.90, up 24.76 per cent.
The stock touched a high of Rs 315 and a low of Rs 295.
The company's IPO, which concluded last month, was subscribed 32.03 times, helping it raise an estimated Rs 550 crore. The company had raised Rs 150 crore from anchor investors.
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Syngene offers integrated drug discovery and development services with capabilities in medicinal chemistry, biology and toxicology.
In January, Biocon concluded a sale of 10 per cent stake in Syngene for Rs 380 crore to IVF Trustee Company, which had valued Syngene International at Rs 3,800 crore.
The stock of Biocon was trading at Rs 462.50, down 0.58 per cent, on BSE at 1200 hours.