In Aleppo province to the north, rebels battled to reverse an advance by the Islamic State group that brought the jihadists to within a few kilometres of Syria's second city.
And Washington said it would resume talks with Russia over ways to avoid military accidents in Syria's increasingly crowded airspace.
In Hama, regime forces seized Atshan village from opposition fighters including Islamists and Al-Qaeda affiliate Al-Nusra Front, state television and the Syrian Observatory for Human Rights said.
With support from Russian air strikes, they appear to be targeting the town of Khan Sheikhun, just across the provincial border in Idlib and on a key highway that runs from Aleppo to Damascus.
More From This Section
The highway is cut by rebel forces in several locations to the north of Khan Sheikhun.
Hama province has been a key target for the Russian strikes that began on September 30, along with parts of the neighbouring provinces of Latakia and Idlib.
In Moscow, Russia's defence ministry said Saturday that its forces had hit 55 Islamic State targets in the past 24 hours.
But rebels and their backers say Hama, Idlib and Latakia have little or no IS presence and accuse Russia of targeting moderate and Islamist opposition fighters more than the jihadist group.
The Observatory also reported heavy fighting on Saturday between regime forces and rebels in northern Latakia province.
Russian warplanes struck both Latakia and Idlib provinces yesterday and today, including a raid in Idlib that destroyed a base belonging to a rebel group that has received US weapons, it said.
The monitor added that rebels were battling to take back a second village from the jihadist group, which is now within 10 kilometres of Aleppo city.