The Syrian Observatory for Human Rights also said that in the northeast, Kurdish fighters seized the town of Tal Barak from jihadists.
Regime forces launched a new wave of aerial and tank bombardment in and around Yabrud, the main town in the Qalamun mountain range and with a mixed Muslim and Christian population, two weeks into a campaign aimed at seizing it from rebels.
The Britain-based Observatory said Saturday's attacks targeted several mountainous areas around Yabrud as well as the town itself, which was once home to some 50,000 people.
Shiite forces from Lebanon's Hezbollah movement are supporting the regular Syrian army in Qalamun. Hezbollah says most of the vehicles used in car bombings of its Lebanon strongholds came from Yabrud.
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"Hezbollah is fighting to close off the border, while the army wants to secure control of the international highway" linking Damascus and the central city of Homs, an activist in Qalamun told AFP by Skype.
Calling himself Amer, he said he believed the bombing had intensified as the army and Hezbollah "fail to make the advance on the ground they want. So they are besieging and punishing Yabrud".
Most of Jobar is under rebel control, and it has seen a massive escalation of fighting since February 9 as the army seeks to crush resistance there, the Observatory said.