Zahran Allouch, the head of the Army of Islam group, was killed in an airstrike that targeted the group's headquarters during a meeting yesterday. He was instantly killed along with other commanders from the ultraconservative Ahrar al-Sham and the Faylaq al-Rahman groups.
His assassination, a month before peace talks are scheduled to begin between the Syrian government and opposition rebel groups, is a blow to insurgents fighting to topple President Bashar Assad and a boost to government forces who have been bolstered by the Russian military intervention in Syria in the past few months.
The Army of Islam took part earlier this month in an opposition meeting held in Saudi Arabia to agree on an opposition delegation that would negotiate with Assad's government representatives in peace talks planned for late January in Geneva.
The Syrian government describes the group as "terrorists" and has said it will not negotiate with such factions.
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The Syrian army claimed responsibility for the airstrike that killed Allouch, although many among the opposition blamed Russia.
"The next stage will witness the liquidation of those leaders who began the uprising," wrote Abu Hassan al-Muhajer, another senior member of the group on Twitter.
Other insurgent groups, including the al-Qaida branch in Syria, the Nusra Front, lamented his killing.
The Army of Islam group swiftly appointed Essam al-Buwaydhani, a field commander known as Abu Hammam, as the new leader of the group, replacing Allouch.
"We are moving forth on the path, and we do not change or alter," the unidentified speaker said, reading from a statement.