The Britain-based Syrian Observatory for Human Rights also said jihadist fighters executed 15 civilians in the northeastern province of Hasakeh.
At least seven children were among those killed by members of the Islamic State of Iraq and the Levant near the town of Ras al-Ain, it said.
The Observatory did not give any immediate toll for today's raids on Aleppo's rebel-held districts, but said regime helicopters dropped barrel bombs on some of the areas.
Aleppo has been split into areas held by the regime and opposition since shortly after fighting broke out in Syria's former economic hub in 2012.
More From This Section
Regime warplanes have waged an aerial offensive on the eastern, rebel-held districts since mid-December, frequently dropping barrel bombs on the area, with hundreds killed in these raids.
The use of barrel bombs -- barrels packed with explosives and scrap metal -- has been condemned by the international community and human rights organisation.
Loyalist forces have made advances on the ground against rebels battling to topple the government of Syrian President Bashar al-Assad, thanks to support from fighters of Lebanon's Hezbollah movement.