The senator's husband, son and another daughter were also wounded in the attack today.
The deputy governor of Gazni province, Mohammad Ali Ahmadi, says insurgents ambushed Senator Rouh Gul Khirzad as she was travelling from Kabul to her home in Nimroz province. Ahmadi says the ambush took place in Gazni's Muqur district, on the main highway from Kabul to the southern city of Kandahar.
Fellow Senator Mohammad Alam says Khirzad's eight-year-old daughter and her bodyguard were killed.