He will take over from Arvind Sethi, who was appointed as the MD and CEO in December 2012, transitioning from his earlier position as an independent director of the company.
In his new role, Ganesh would be responsible for steering the growth of the organisation as it continues to be positioned as an asset management firm with strategic presence in chosen segments.
Ganesh would be assuming the charge on June 29, 2015.
Prior to joining Tata Asset Management, he was Managing Director of Blackrock Inc.
"His ability to lead high performing teams to the next level of excellence and growth will benefit our organisation," Tata Asset Management Chairman F N Subedar said in a statement.
The company has an asset base of about Rs 28,000 crore, including an overseas AUM of over Rs 1,800 crore.