"All of us technology companies need to create some tools that help diminish the volume of fake news," the US tech giant boss told the Daily Telegraph in an interview.
"We must try to squeeze this without stepping on freedom of speech and of the press, but we must also help the reader.
"Too many of us are just in the complain category right now and haven't figured out what to do."
But Cook, who met British Prime Minister Theresa May at Downing Street on Thursday, said governments should also introduce a public information campaign.
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He added: "We are going through this period of time right here where unfortunately some of the people that are winning are the people that spend their time trying to get the most clicks, not tell the most truth.
"It's killing people's minds in a way."
Fake news - fabricated reports designed to promote a particular agenda - came to prominence during last year's US presidential election campaign.
Facebook in particular has come under pressure for failing to take action, and last month modified its system for showing trending topics.