"Binge drinking is neurotoxic and our data support that there may be serious cardiovascular consequences in young adults," said Shane A Phillips, senior author and associate professor and associate head of physical therapy at the University of Illinois at Chicago.
College students age 18 to 25 years old have the highest rates of binge drinking episodes in US, with more than half engaging in binge drinking on a regular basis.
Prior studies have found that binge drinking among adults age 40 to 60 years old is associated with an increase in risk for stroke, sudden cardiac death and heart attack, but the effect on younger adults has not been studied.
Binge drinking was defined as consuming five or more standard size drinks in a two-hour period for males and four or more standard size drinks in a two-hour period for females.
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On average, the students who binge drink had six such episodes each month over four years. Abstainers were defined as having consumed no more than five drinks in the prior year.
The study found that the binge drinkers had impaired function in the two main cell types (endothelium and smooth muscle) that control blood flow.
Binge drinkers were not found to have increased blood pressure or cholesterol, which are well-established risk factors for heart disease; however, both high blood pressure and cholesterol cause changes in vascular function similar to what the students demonstrated.
"It is important that young adults understand that binge drinking patterns are an extreme form of unhealthy or at-risk drinking and are associated with serious social and medical consequences," Mariann Piano, co-author of the study and professor and head of the department of biobehavioural health science at the University of Illinois, said.