The girls were taking a bath to beat the heat when the mishap occured near Amrutamanehi village about 25 Km from here.
The victims, all from dalit community, were students of a government-aided high school in the village.
As the girls raised an alarm, a group of fishermen rushed to their rescue. One girl was saved and the body of another fished out from the Brahmani River while fire brigade personnel were pressed into service to trace the two other missing girls.