The report yesterday quotes Iran's deputy foreign minister Abbas Araghchi as saying he raised the issue Friday during a meeting with an American delegation in Vienna, on the sidelines of a meeting on 2015 nuclear deal.
"We raised the issue of the release of Iranians who are detained under the meaningless accusation of bypassing sanctions," on Iran, Araghchi was quoted as saying. He did not elaborate.
Earlier on Friday the White House threatened "new and serious consequences" for Iran unless it releases all US citizens who are detained there.
Washington is urging the return of former FBI agent Robert Levinson, who disappeared in Iran in 2007 and Princeton graduate student Xiyue Wang, who was arrested last year.
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Xiyue's confinement became public this week after Iran's judiciary announced his 10-year sentence.
Later yesterday the spokesman for Iran's foreign ministry, Bahram Ghasemi, rejected the US demand calling it "intervention" in Iranian internal affairs, the official IRNA news agency reported.
However he added that Levinson left Iran after visiting Iran and Tehran has no information about him.
Ghasemi also reiterated the demand for the "quick" release of Iranian detainees in the US, and said one of the wanted Iranian by the US has already died abroad. He did not elaborate.
Also detained by Iran are Iranian-American businessman Siamak Namazi and his 81-year-old father, Baquer Namazi. They were taken during the Obama administration and are also serving 10-year sentences.