"Sachin's retirement is a big loss to world cricket. He is not only an amazing player but a great human being as well. I have a lot of respect for him," Saqlain told PTI Bhasha.
Tendulkar will bid adieu to the game after playing his 200th Test against the West Indies in Mumbai next month.
Saqlain, who would always be remembered for his 10-wicket match haul that was instrumental in his team handing a 12-run defeat to India in the 1999 Chennai Test match, said it was an "honour" playing against Tendulkar and he enjoyed bowling to the legendary batsman.
Saqlain, famous for inventing the 'doosra', had been training the West Indies slow bowlers on the art of bowling the delivery at a special camp in Barbados ahead of their tour to India.
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Saqlain was part of a high performance camp in Barbados, where he shared tips on how to breach the defence of Indian batsmen. However, Saqlain, a veteran of 49 Tests and 169 ODIs, will not be travelling with the Caribbean team to India as he will take up the job of spin coach with Bangladesh.
"India, at this time, is the best team in the world. They have a winning mentality. It's difficult to beat them at home," he added.