Both France and Egypt have been leading targets for Islamist extremists in recent months.
In October, the Islamic State group claimed responsibility for bombing an A321 plane belonging to Russian charter company Metrojet that crashed into the Sinai desert on its way from the Egyptian resort of Sharm el-Sheikh to St Petersburg, killing 224 passengers and crew.
Experts say the chances of a mechanical malfunction in the case of today's Egyptair disappearance are slim.
In addition, the A320 has an excellent safety record as the best-selling, medium-range airliner in the world. An A320 takes off or lands every 30 seconds around the world, Feldzer said.
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"It's a modern plane, the incident happened in mid-flight in extremely stable conditions. The quality of the maintenance and the quality of the plane are not in question in this incident," Jean-Paul Troadec, former director of France's aviation Bureau of Investigation and Analysis, told Europe 1 radio.
Experts also say it is unlikely that the plane was shot down from the ground, as was the case with the Malaysia Airlines Flight 17 that went down over Ukraine in July 2014, or from the sea as occurred in July 1988 when the US Navy blew up an Iran Air passenger flight by mistake.
The Egyptair plane was flying at 37,000 feet (11,000 metres) and disappeared about 130 nautical miles off the Greek island of Karpathos.
That would put it out of reach of portable rocket launchers used by several militant groups in the Middle East.
The region around northern Egypt, including the Israeli and Gazan coastlines, is "one of the most monitored regions in the world, including by satellite. It would be very difficult to hide this kind of information," he added.
That leaves a terrorist attack as the most likely possibility, not least because it appears that no distress signal was sent from the aircraft.
"A technical problem, a fire or a motor malfunction, doesn't cause an instantaneous accident and the crew has time to react," said Troadec.
If a bombing is established, the question for investigators will be how a device was smuggled aboard a flight taking off from France's busiest airport, Paris Charles de Gaulle, where security has been on high alert since last year's jihadist attacks in the French capital.