A team led by Jong Bhak of the Personal Genomics Institute in Suwon unravelled the genome of the Amur tiger, and compared it against those of a white Bengal tiger, the African lion, a white African lion and the snow leopard.
The comparison yielded a string of genes highlighting shared characteristics among these close but distinct species.
They include common genes pointing to extreme muscle strength and an ability to metabolise a "hypercarnivorous" diet.
The genomes, reported in the journal Nature Communications, point to a "rich and diverse" data source for helping conservationists, Bhak's team said.
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Of the nine subspecies of tiger, they reported, four were wiped out in the wild in the last century -- the Javan, Balinese, South China and Caspian tigers.
"The current estimates of wild tigers range from just 3,050 to 3,950 individuals," they said.
"It is postulated that without conservation measures, tigers will soon become extinct in the wild.