The 55-year-old "A Bigger Splash" star is seen with actor Giancarlo Esposito in the first official image of the film, reported Entertainment Weekly.
Directed by Bong Joon-Ho, the movie revolves around a young girl, Seohyun An, who fights to prevent a powerful multinational company from kidnapping her best friend - who is a massive animal named Okja.
The film also star Jake Gyllenhaal, Paul Dano, and Steven Yeun.
The director Joon-Ho said, "I want to show the beauty that can exist between man and animal, and also the horror between them."