The LPG tanker driver, who was injured, was hospitalised.
The collision on the Tiruchirapalli-Thanjavur state highway resulted in kerosene spilling on the road from a crack in the tanker.
Fire service personnel immediately rushed to the spot, removed the LPG cylinders to safety and then plugged the leak, preventing a major accident, they said.
The accident took place near Thuvakudi and Vazhavandhan Kottai, where Indian Oil Corporation's godown is located.