The Paramount Pictures film is based on Robert Carlock's adaptation of "The Taliban shuffle: strange days in Afghanistan and Pakistan", reported Deadline
The story revolves around Kim Barker, an American reporter who navigated the male-dominated world of journalism in Afghanistan and Pakistan.
Fey, 45, will play Barker, who was the Chicago Tribune's south asia bureau chief from 2004-09.
The film also stars Margot Robbie and Martin Freeman, Alfred Molina, Nicholas Braun, Christopher Abbott, Sheila Vand, Stephen Peacocke, Evan Jonigkeit and Billy Bob Thornton.
Fey is also producing with Lorne Michaels and Ian Bryce.