"Zombieland" helmer Ruben Fleischer will direct the movie from Scott Rosenberg and Jeff Pinkner's script, reported The Guardian.
Hardy, 39, will play Eddie Brock, a freelance photographer who becomes infected by an alien lifeform that needs a host in order to survive.
The "Mad Max: Fury Road" actor was last seen on the small screen in "Taboo" and will next feature in this summer's second world war drama "Dunkirk".