The 36-year-old star will be a part of the play, which will be directed by Kenneth Branagh, to raise 20 million pounds for the theatre academy, reported FemaleFirst.
"'Hamlet' presents almost limitless possibilities for interpretation. I can't wait to explore them, with this great cast, at RADA. Kenneth Branagh and I have long talked about working on the play together, and now felt like the right time, at the right place.
"To be guided through it by him as a director, an expert and a friend, is our great good fortune. The performing arts exist to bring people together, not to break or keep them apart," Hiddleston said.
The "Avengers: Infinity War" actor added, "I hope the funds raised by the production will help RADA continue to provide a wider field of equal opportunity to train actors, stage managers and technical theatre artists, from every background, to a standard of excellence and professionalism. We need to keep the doors open for everyone.