Masur Ahmad Lary was arrested from Maharajgunj area of Kathmandu, said a senior police officer of Kathmandu Metropolitan Police Office.
The police was searching the hotelier after narcotic drugs were found inside a parcel dispatched by him from Kathmandu to the Netherlands during a security check at Frankfurt Airport in Germany, police said.
Lary is the owner of Kathmandu's five-star Everest Hotel, which remained closed after its building developed major cracks in 2015 earthquakes.
He has been operating the hotel in Kathmandu for the last 30 years.