Sania and Soares lost 2-6 2-6 in just 56 minutes against the unseeded German-Dutch combination at the Rolland Garros.
The top seeds did not have best of starts as Groenefeld and Rojer broke the Indo-Brazilian pair in the their first service game to race to a 3-0 lead in the first set.
In fact, the unseeded Groenfeld and Rojer combination were by far the bestter side on the court in all aspects of the game in the opening set.
The second set was no different as Groenfeld and Rojer looked in total control of the proceedings.
The second set went on serves till the fourth game before Groenfeld and Roger broke their opponents in the fifth game to take a 3-2 lead.
The German-Dutch pair broke Sania and Soares again in the seventh game and then held on to their serve to pocket the match and a place in the second round, where they will be up against Yung-Jan Chan of Chinese Taipei and John Peers of Australia.