Two Israeli soldiers were said to be using the app when they mistakenly drove into the Qalandiya refugee camp overnight, sparking clashes as security forces deployed to rescue them that killed one Palestinian and wounded 15 people.
Waze, the Israeli-developed navigation app acquired by Google for more than USD 1 billion in 2013, said the soldiers themselves were at fault.
"(Waze) includes a specific default setting that prevents routes through areas which are marked as dangerous or prohibited for Israelis to drive through," the company said in a statement to AFP.
"There are also red signs on the road in question that prohibit access to Palestinian-controlled territories (for Israelis). It is the responsibility of every driver to adhere to road and traffic signs and obey local laws."
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The entry of the soldiers led to fierce clashes, with the two fleeing their jeep and Israeli forces staging a rescue. The two soldiers were later recovered unharmed.
According to an Israeli police spokeswoman, Palestinians threw homemade explosives and shot at the rescue team, which also opened fire.
Five Israeli border police were also wounded, one of them seriously, police said.
"Waze has and is continuing to work directly with the relevant authorities to decrease such mishaps from occurring, but unfortunately there is no ability to prevent them altogether as ultimately some prudence is in the driver's hands," it said in its statement.