Trump, who was not accompanied by the First Lady, departed Joint Base Andrews shortly before 9 PM on a trip that will also see him hold talks with several world leaders.
"Will soon be heading to Davos, Switzerland, to tell the world how great America is and is doing. Our economy is now booming and with all I am doing, will only get better...Our country is finally WINNING again!" he tweeted shortly before getting on the helicopter that took him to the air base.
"We're going to the World Economic Forum to share President Trump's economic story and to tell the world that America is open for business," said Trump's chief economic adviser Gary Cohn.
Trump, who has left the Paris climate change accords, abandoned the Trans-Pacific Partnership, threatened to scrap the North American Free Trade Agreement (NAFTA) and just imposed heavy duties on imported washing machines and solar panels, will have his work cut out convincing defenders of global free trade that he is on their side.
On the diplomatic front, Trump is scheduled to meet with Israeli Prime Minister Benjamin Netanyahu weeks after recognizing Jerusalem as Israel's capital, and British premier Theresa May, which comes as US-UK relations are unusually strained.
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