Trump, 70, and his family left New York City for Washington, this time not flying in his private plane that bears his name but in a military jet headed to Andrews Air Force Base in Maryland near the nation's capital.
Joined by his family, wife Melania, daughter Ivanka and sons Don and Eric, Trump will take the oath of office as the leader of the world's most powerful nation tomorrow as hundreds of thousands of people descend on Washington to both support and protest his inauguration.
Trump, who enters the White House with the promise of transforming US politics over the next four years, began his day today with tweeting: "The journey begins and I will be working and fighting very hard to make it a great journey for the American people. I have no doubt that we will, together, MAKE AMERICA GREAT AGAIN!"
Trump's swearing-in tomorrow noon, a date and hour set by the US Constitution, will be attended by his unsuccessful Democratic challenger Hillary Clinton, three former presidents and numerous other dignitaries.
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hinted that he could split his time between the White House and New York City, returning to his Trump Tower in Manhattan for the weekends.
His wife Melania, however, will stay on in New York with their 10-year-old son Barron as he finishes his school year in the city.
Trump's daughter Ivanka and her husband Jared Kushner will move to Washington with their children, as Kushner takes the role of senior adviser to the President.
The 35-year-old businessman-turned-political strategist played a key part in his father-in-law's presidential campaign.
Ivanka, touted to be the most powerful First Daughter, has said she plans to take time to settle her three young children into their new home and schools in Washington.
Just hours before Trump departed New York City, for the final time as a private citizen, he took to Twitter to quote a American Christian evangelist Reverend Franklin Graham to say he is not the one to have divided the country and pledged to work hard for the American people.
After taking over from outgoing US President Barack Obama, Trump is widely expected to sign a number of decrees on Friday and then on Monday, on issues ranging from immigration, Obamacare to environment.
Sources close to Trump said that his inauguration speech will last about 20 minutes, the same as Obama's first inaugural in 2009.