The three-story Tudor-style home in Queens that Trump's father, Fred, built in 1940 is now a rental available on Airbnb that anyone can stay in for USD 725 a night.
It was auctioned off to an unidentified buyer in March for USD 2.14 million, its second time going up for auction.
The international anti-poverty organisation Oxfam rented it Saturday and invited four refugees to talk with journalists.
"We wanted to send a strong message to Trump and world leaders that they must do more to welcome refugees," said Shannon Scribner, acting director for the humanitarian department of Oxfam America.
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Trump lived in the house on a tree-lined street of single-family dwellings until he was about 4, when his family moved to another home his father had built nearby.
"Knowing Donald Trump was here at the age of four makes me think about where I was at the age of four," said Ali, her smiling face framed by a dark gray hijab. "We're all kids who are raised to be productive citizens, who have all these dreams and hopes."
Ali was three when she arrived in the United States from Yemen, where her parents had fled when war broke out in their native Somalia. Ali said she remembered Trump as an entertaining character on "The Celebrity Apprentice," but has since changed her opinion.
Down the hall, Ghassan al-Chahada, 41, a Syrian refugee who arrived in the US with his wife and three children in 2012, sat in a room with bunk beds and a sign on the wall that said it likely was Trump's childhood bedroom.
"Before the conflict began in Syria we had dreams of coming to America," al-Chahada said. "For us, it was a dream come true."
Al-Chahada said his life changed when Trump signed the ban that barred people from Syria and five other countries, from entering the United States.
He looked out the window into the front yard and thought about what he would say to the president.
"I would advise him to remember, to think about how he felt when he slept in this bedroom," al-Chahada said. "If he can stay in tune with who he was as a child, the compassion children have and the mercy, I would say he's a great person.