"Russia started their anti-US campaign in 2014, long before I announced that I would run for president," Trump tweeted, pointing to details of the indictment as evidence of his name being cleared.
"The results of the election were not impacted. The Trump campaign did nothing wrong - no collusion!"
US Special Counsel Robert Mueller indicted the 13 Russian nationals, as well as three companies, for running a secret campaign to tilt the presidential election.
Trump has repeatedly dismissed claims of Russian interference as "fake news" designed to take away from his election victory over Hillary Clinton.
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Deputy Attorney General Rod Rosenstein said the indictments contained "no allegation" that any American was a knowing participant in the meddling, and said there was no judgement on whether the election outcome was affected.
In a separate White House statement reacting to the indictments, Trump urged his fellow citizens to "unite as Americans to protect the integrity of our democracy and our elections."
"Its time we stop the outlandish partisan attacks, wild and false allegations, and far-fetched theories, which only serve to further the agendas of bad actors, like Russia, and do nothing to protect the principles of our institutions.
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