Rached Ghannouchi, head of the moderate Islamist party Ennahda that heads a coalition cabinet, slammed the opposition as "anarchists" for demanding the resignation of Tunisia's elected government.
Three weeks into a crisis triggered by the assassination of opposition leader Mohamed Brahmi, Ghannouchi ruled out the formation of a government of technocrats as demanded by the opposition.
"That would spell danger for the country, it would push us towards the void and finish off the democratic experiment in Tunisia," he said.
"In democracies, governments don't fall because of sit-ins or demonstrations but after elections or a lost vote of confidence in parliament," said the Ennahda chief.
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Ghannouchi said a second round of negotiations between the government and the powerful UGTT trade union aimed at hammering out a compromise would be held on Monday, after an initial meeting this week failed to make any headway.
The Egyptian army's July 3 overthrow of elected Islamist president Mohamed Morsi after massive street protests had already sharpened divisions in Tunisia, and both sides are wary of sliding into the turmoil of the fellow North African state.
Yesterday, more than 500 people were killed in nationwide clashes following a crackdown by Egyptian security forces on Morsi supporters.
"What's happening in Egypt shows the need for all political parties in Tunisia to sit down at the negotiating table with a commitment to legitimacy and democracy... And without incitement to confrontation," Tunisian President Moncef Marzouki said.