The migrants, who included 10 children, died yesterday when the boat carrying them on a bid to reach EU member Greece from Turkey sank in the Aegean in the latest deadly disaster on the route.
The tragedy happened a day before Turkish Prime Minister Ahmet Davutoglu held talks in Brussels Monday with EU leaders to find a comprehensive solution to the migrant crisis.
The owner of the boat, named as KC, and the suspected people smuggler, YY were detained by police in the Didim district of the Aydin region of western Turkey, the Dogan news agency reported.
Fifteen people were saved after the sinking of the boat while rescue efforts were still underway to find two more missing, the report said.
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Turkey is the main launch pad for most of the more than one million refugees and migrants who have crossed into Europe since early 2015, and is under pressure to curb the huge flow.
According to the International Organisation for Migration (IOM), 125,819 people crossed the Aegean Sea from Turkey to Greece so far this year to March 3 while 321 died on the way.