Analysts are predicting that the outcome of the referendum on the new constitution to create an executive presidency is no foregone conclusion and Erdogan will criss-cross Turkey in the next two months to mobilise voters.
He kicked off the campaign -- after returning from a tour of Gulf countries -- in the eastern city of Kahramanmaras, one of the areas that gave him the most votes in the 2014 presidential polls.
"April 16 will be the night of carrying out reform in Turkey," he added.
Opponents fear that the touted presidential system -- which would discard the post of prime minister for the first time in Turkey's history -- would cement one-man rule in the country under Erdogan.
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But Erdogan argued that the new system would clearly delineate between the executive and the legislature, so that "everyone can concentrate on their own business".
He explained that the new system would mean there would be no return to the "old Turkey" of short-lived coalition governments, which, he said, sometimes lasted just 25 days and had an average survival rate of 16 months.
Relations with the West and have strained in the wake of the July 15 coup aimed at ousting Erdogan from power, which was followed by a crackdown whose magnitude is unprecedented in modern Turkish history.
The president reaffirmed he would approve legislation reimposing the death penalty in Turkey -- if it was approved by parliament after the referendum.
Reimposing the death penalty, abolished in 2004, would spell the end of Turkey's embattled bid to join the European Union.
But Erdogan said he was not bothered by what the EU had to say about the issue.
"What interests me is what Ahmet, Mehmet, Ayse, Fatma say," he said, using traditional Turkish Muslim names. "I am interested in what Allah (God) says!"
Erdogan is expected over the weekend to visit more cities in the east where he enjoys soaring support including Malatya, Elazig and Gaziantep.
The legislation was pushed through by the ruling Justice and Development Party (AKP) with the help of the opposition Nationalist Movement Party (MHP). Prime Minister Binali Yildirim said today the two parties could have joint campaign events.