"We are working for this region to be declared no-fly zone," Erdogan said at the G20 meeting in China, referring to the land extending from Jarabulus to Azaz in northern Syria seized from IS jihadists.
"This is my proposal to Mr Putin and Mr Obama. This can be done with coalition forces," he added in televised comments.
Turkey launched an ambitious operation inside Syria on August 24, sending tanks and special forces in to back opposition fighters.
Ankara has often called for a safe-zone inside Syria, backed up with a no-fly zone, as it is currently hosting more than 2.5 million refugees who fled the over five-year civil war.
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In China, Erdogan said he told all world leaders at the Antalya summit last year that "in Syria a safe zone could be set up... And we could solve the refugee crisis."
He added: "Now in this summit, to all of our friends, we have brought up this issue and told them this."
"We are currently cooperating with Russia in the region of Aleppo. We are working for a ceasefire to be declared in the region... And the people of Aleppo saved from the bombs.