A senior US military commander had been quoted by American media as saying that the turmoil in post-coup Turkey could affect its role in the US-led coalition fighting IS jihadists in Syria.
But Foreign Minister Mevlut Cavusoglu told reporters in Ankara that he found such statements "ridiculous" and "unfortunate".
Turkish forces face the challenge of fighting both IS jihadists and guerrillas from the Kurdistan Workers' Party (PKK).
Turkey has embarked on a major military reshuffle after the putsch, which Ankara blames on US-based preacher Fethullah Gulen and his followers.
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Authorities accuse the reclusive cleric of building a "parallel structure" inside Turkey.
The government has ordered the discharge of 149 generals -- nearly half the armed forces' entire contingent of 358 -- for complicity in the putsch bid. Almost all of these generals are currently under arrest.
"On the contrary. When we weed them (pro-Gulenist elements) out, our army will first of all be more dynamic, cleaner and more effective."
The minister ridiculed the idea that it was only pro-Gulen elements in the military that wanted to fight IS militants.
"We don't find such assessments right," he said.
Turkey, which has itself been hit by deadly attacks blamed on jihadists, regularly targets IS positions in Syria with artillery fire.
Its Incirlik air base in the south also hosts US and other coalition warplanes launching deadly raids on jihadists in Syria.
According to US media, Central Command chief General Joseph Votel said the coup bid and subsequent round-up of generals could affect American military cooperation with Turkey.