21-year-old, who turned pro midway through this season, surged way ahead of the rest of the field despite the tough weather conditions as she shot the day's best score of 73 to win her second title in five starts.
The next score was 79 by three players, including third- placed Saaniya Sharma, Gaurika Bishnoi and Ankita Tiwana.
Siddhi Kapoor (81) was second, while Saaniya Sharma (79) was third.
Tvesa became the fourth player to win multiple titles this season after Vani Kapoor (3), Amandeep Drall (2) and Gursimar Badwal (2).
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Second placed Siddhi, who shared the lead with Tvesa for the first two days, carded 81, including two birdies, seven bogeys and two doubles and aggregated 228.
Afshan Fatima, who had a share of the lead after the first round, carded a second successive 80 and finished fourth at 234, while Gursimar Badwal (82) and Smriti Mehra (82) were tied fifth.
Gaurika Bishnoi (79) reclaimed her top position on the Hero Order of Merit despite finishing seventh and Ankita Tiwana (79) was eighth.
Amandeep's absence helped Gaurika to get back to the top of the Order of Merit. Gaurika (Rs. 9,06,400) leads Amandeep (Rs. 8,77,500) by just over 30,000, while Gursimar (Rs. 7,39,200) is third and Saaniya (Rs. 6.76,000) is at fourth.
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