He made the announcement on Twitter itself by writing: "Today, after 4 years of user/business momentum in India & the region, I'm sharing my intention to move on to new opportunities, same mission."
Jaitly, who played a key role in expanding the company's operations in India, further said leading Twitter India and expanding @TwitterMedia across Asia Pacific and Middle East was "leadership experience of a lifetime".
While he did not disclose his next destination, he said "a personal/civic calling takes me to Chicago, I'll spend significant time in India/Asia, drawing on my past to further tech's promise".
Jaitly has also been associated with Knight Foundation and College Summit and was co-founder and CEO of Michigan Corps.
When contacted, a Twitter India spokesperson said: "We thank Rishi Jaitly for his contributions, entrepreneurship and leadership over the past four years at Twitter. He was our first person on the ground to bring Twitter into the high-growth Indian market".
"There will be a smooth transition as his last day is in late November after which he will move back to the US," the spokesperson added.
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