An F4 aircraft that took off for a training flight at 1158 IST crashed at 0120 IST in the central Anatolian city of Konya, the Turkish Armed Forces said in a statement on its website.
The army gave no further information on the cause of the incident. Both pilots on board were killed.
Turkish media said that the the flight was part of a joint Turkish-Azerbaijani military exercise which kicked off on Monday.
The fighter jets of the Turkish army - a force second only to the United States in the NATO alliance in terms of size - has in recent years played an active role in patrolling its volatile borders with Iraq and Syria.
The country in 2009 has modernised its ageing fleet of F-4s, in use since 1970's, with the intention of keeping them until 2020.