External Affairs Ministry said Indian Mission in Jeddah was continuously monitoring the situation after the stampede.
More than 1.5 lakh Indians are among over two million pilgrims performing Haj in Mecca this year.
"Our Mission in Jeddah is continuously monitoring the situation in Makkah following tragic stampede," External Affairs Ministry Spokesperson Vikas Swarup tweeted.
Officials in Jeddah said that two Indian nationals were among the injured.
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The Saudi civil defence authority said 453 people from different nationalities have died in the tragedy. Rescue operations were underway after the stampede in Mina, where pilgrims were performing the symbolic stoning of the devil by throwing stones at the three pillars.
Prime Minister Narendra Modi has expressed pain at the loss of lives in stampede in Mecca and conveyed his condolences to the families of the deceased.
"Distressing news from Mecca," tweeted Modi, who is in the USA on a six-day visit.
Over 700 people have been injured in the stampede which occurred days after a massive crane collapse in Mecca Grand Mosque killed 115 people, including 11 Indians.