According to official sources, a house in the Indian Embassy complex collapsed, killing the daughter of a CPWD employee, Madan.
Death of another Indian was reported at Bir Hospital, the sources said.
However, the details of the second Indian victim is not immediately known.
Nepal was today struck by the worst earthquake in 80 years, leaving nearly 1,500 people dead in flattened houses and buildings including the iconic Dharhara tower and renowned Darbar Square in the heart of the capital.