The incident took place after drivers and helpers, who were agitating for pay hike, allegedly attacked the transport firm office and tried to set it on fire, Deputy Superintendent of Police Anthony Tirkey said.
The protesters, who had gathered at the company office premises, suddenly turned violent as negotiation for their pay hike reportedly failed and also pelted stones at policemen deployed at the site as a precautionary measure, he said.
At least 16 persons, including six police personnel, were injured during the clash and several of them were undergoing treatment at VSS Medical College and Hospital at Burla, he said.
The deceased were identified as driver Abinash Soren of Hurduna in Purulia district of West Bengal and Gaurab Hembram of Sareipara in Mayurbhanj district, the DSP said.
The six police personnel injured in the clash were a Havildar, a sub-inspector, an assistant sub-inspectors and three constables, he said.