Fort Myers police are questioning three people possibly connected to the shooting which occurred around 12-30 am in the parking lot of Club Blu Bar and Grill in Fort Myers, Florida.
Their identities have not been released. Police also have not released any of the victims' names.
Three people remained hospitalised, Cherly Garn, a spokeswoman for Lee Memorial Health System, said. All others were treated and released. Ages of the patients ranged from 12 to 27, Garn said.
"We are deeply sorry for all involved. We tried to give the teens what we thought was a safe place to have a good time," the club said.
More From This Section
"It was not kids at the party that did this despicable act," it said.
Police said officers responded to reports of a shooting in the club's parking lot to find several victims with injuries ranging from minor to life-threatening, police said.
Detectives were trying to determine the exact number of victims and said it appeared between 14 and 16 people were injured.
Two others were killed, local station WINK-TV reported, quoting police as saying.
According to witnesses the moments outside the club was like a "mad house".
One woman who lives two blocks from Club Blu said she heard multiple gunshots.
People were crying and screaming, she wrote on her Facebook Page, adding that many were being carried on ambulances to area hospitals.
"While we are still learning the details about what happened this morning, we know that some of the victims of this terrible incident were children. We will continue to pray for the victims and their families," the statement said.
"The Indian Consulate in Houston is in close contact with
the family of the deceased -- Mr Srinivas Kuchibhotla. In their hour of grief, we are providing all help and assistance to the bereaved family. Arrangements are being made to transport his mortal remains to India," Mathur said.
In New Delhi, External Affairs Minister Sushma Swaraj expressed shock over the incident and said two Indian consulate officials from Houston have been rushed to Kansas to render all possible assistance.
"I am shocked at the shooting incident in Kansas in which Srinivas Kuchibhotla has been killed. My heartfelt condolences to bereaved family," she tweeted.
"I have spoken to Indian Ambassador in US Navtej Sarna. He informed me that two Indian Embassy officials have rushed to Kansas," she said.
External Affairs Ministry Spokesperson Vikas Swarup said Kuchibhotla and Madasani hailed from Hyderabad and Warangal.
They will also meet the community members in Kansas, he said.
According to Garmin, Kuchibhotla and Madasani worked in the company's aviation systems.
"Unfortunately, two associates on our Aviation Systems Engineering team, Srinivas Kuchibhotla and Alok Madasani, were shot. We are devastated to inform you that Srinivas passed away and Alok is currently recovering in the hospital," Garmin said.
A 2014 post on LinkedIn said Madasani was an aviation programme coordinator manager at Garmin.
The shooter, a navy veteran with inactive pilot license and air traffic controller certificate, told a bartender in Clinton, Missouri, where he was hiding after the shooting that he killed two Middle Eastern persons, local media reported.
He has been charged with premeditated first-degree murder and his bond has been set at USD 2 million.
Friends of Kuchibhotla have set up a GoFundMe page to help raise funds for sending his remains to India.
"Srini was the kindest person you would meet, full of love, care and compassion for everyone. He never uttered a word of hatred, a simple gossip, or a careless comment. He was brilliant, well mannered and simply an outstanding human being," the fund raising page said.
"His wife Sunayana and his family are now faced with incredible grief and a multitude of expenses," it said.