The tempo, packed with labourers, was going to Girnare from Jategaon in this district, when its tyre bust causing the vehicle to overturn, an official of Harsul Police Station said.
Tempo driver Arjun Sole (45), a resident of Jategaon, and Dharma Bahate (48), died in the accident, police said.
The injured, with four of them in serious condition, were admitted to Nashik Civil Hospital, the official said.