Salduram Anchale (52) and Sunil Jain (25) were nabbed from Sikhsod and Tadoti police station area in the district, about 125 km from here, police officials told PTI by phone.
Acting on a tip-off, a joint team of BSF and district police launched a combing operation in the area as part of anti-Naxal campaign "Meghdoot".
The two ultras were cornered and taken into custody, they said.
Anchale and Jain, wanted in cases related to murder, attempt to murder and arson, among others, had been on police search list for a long time, the officials said, adding their interrogation was on.